@article {1703,
	title = {Genes for regeneration},
	journal = {eLife},
	volume = {3},
	year = {2014},
	month = {2014/04/15},
	pages = {e02517},
	publisher = {eLife Sciences Publications, Ltd},
	abstract = {FoxA, an evolutionarily conserved gene involved in the development of the digestive system in many animals, has an important role in regeneration in flatworms.},
	keywords = {Pharynx, planaria, regeneration, single-organ regeneration, stem cell},
	isbn = {2050-084X},
	url = {https://dx.doi.org/10.7554/eLife.02517},
	author = {Rossant, Janet}
}
@article {1675,
	title = {Identification and characterization of a novel multifunctional placenta specific protein 8 in <i>Dugesia japonica</i>},
	volume = {613},
	year = {2017},
	month = {2017/5/20/},
	pages = {1 - 9},
	abstract = {<p>AbstractPlacenta specific protein 8 (Plac8) has been well studied in vertebrates, yet little is known in invertebrates. In this study, a novel Plac8 from the planarian Dugesia japonica was identified and its functions in immune responses and development were characterized. Our results show that Djplac8 was expressed in the pharynx, epidermis and intestine of intact adult planarian. The expression of DjPlac8 increased significantly upon lipopolysaccharide (LPS) challenge, and inhibited the growth of the Gram-negative bacteria (Escherichia coli and Pseudomonas aeruginosa), suggesting the role of Plac8 in immune response. Spatial and temporal expression and distribution of DjPlac8 mRNA in regenerated planarians indicates that DjPlac8 was mainly expressed in the pharynx. In situ hybridization also revealed the elevated expression of the DjPlac8 gene in the embryonic pharynx, germ band and parenchyma cells, indicating an important role in embryonic development of D. japonica. When DjPlac8 was deactivated by RNA interference-mediated knockdown, the head of planarians underwent abnormal development. In summary, we identified DjPlac8 as a novel multifunctional protein that plays essential roles in immune response and development of planarians.</p>
},
	keywords = {Development, Immunity, Pharynx, Plac8, planarian},
	isbn = {0378-1119},
	url = {http://www.sciencedirect.com/science/article/pii/S0378111917301130},
	author = {Pang, Qiuxiang and Gao, Lili and Bai, Yun and Deng, Hongkuan and Han, Yu and Hu, Wenjing and Zhang, Yanhui and Yuan, Shanhang and Sun, Wenping and Lu, Yiqian and Zhang, Xiufang and Liu, Baohua and Zhao, Bosheng}
}
