@article {1738, title = {Gene organization and expression of a neuropeptide Y homolog from the land planarian Arthurdendyus triangulatus}, journal = {J Comp Neurol}, volume = {454}, year = {2002}, month = {2002 Dec 02}, pages = {58-64}, abstract = {

Neuropeptide Y is one of the most widespread regulatory peptides within the vertebrate nervous system and shares the C-terminal motif [FY]-x(3)-[LIVM]-x(2)-Y-x(3)-[LIVMFY]-x-R-x-R-[YF] with pancreatic polypeptide, peptide YY, and fish pancreatic peptide Y. All four peptides are believed to have arisen from a single ancestral gene through successive gene duplication events in vertebrates. The origin of this peptide family may date back further still; similarly sized peptide transmitters with an identical C-terminal motif have been identified in molluscs and flatworms and designated neuropeptide F (NPF). Cloning of the npf gene from the parasitic flatworm Moniezia expansa identified some unusual features within the peptide precursor organization but, at the same time, provided support for an evolutionary relationship of npf and npy genes through the presence of a single intron at a conserved position. To extend the analysis of the evolutionary relationships between invertebrate NPF and vertebrate NPY family peptides, the NPF precursor from the turbellarian Arthurdendyus triangulatus was characterized. Sequence analysis revealed the npf transcript to be 362 base pairs in length encoding a single open reading frame of 81 amino acids. The precursor comprises a signal peptide followed by the mature peptide of 36 amino acids in length, terminating in the typical invertebrate GRPRF motif, followed by a carboxyterminal glycyl extension. The NPF precursor of A. triangulatus shows significant similarities to the vertebrate NPY peptides. Indeed, the N-terminus of A. triangulatus prepro-NPF corresponds more closely to that of the vertebrate peptide homologs than to that of other invertebrate NPFs isolated to date. Immunocytochemical localization studies have demonstrated NPF immunoreactivity throughout the nervous system of A. triangulatus, particularly in association with muscular structures. The data support an early evolutionary origin for this peptide transmitter family within the nervous system of basal bilaterians.

}, keywords = {Amino Acid Sequence, Animals, Base Sequence, DNA, Complementary, Genomic Library, Helminth Proteins, Introns, Molecular Sequence Data, Nervous system, Neuropeptide Y, Organ Specificity, planarians, Reverse Transcriptase Polymerase Chain Reaction, Sequence Analysis, DNA, Sequence Homology, Amino Acid}, issn = {0021-9967}, doi = {10.1002/cne.10440}, author = {Dougan, Paula M and Mair, Gunnar R and Halton, David W and Curry, W James and Day, Tim A and Maule, Aaron G} } @article {1646, title = {Not your father{\textquoteright}s planarian: a classic model enters the era of functional genomics}, volume = {3}, year = {2002}, month = {2002//}, url = {http://dx.doi.org/10.1038/nrg759}, author = {Newmark, P. A. and Sanchez Alvarado, A.} } @article {1634, title = {Epsilon-tubulin is an essential component of the centriole}, volume = {13}, year = {2002}, month = {2002//}, url = {http://dx.doi.org/10.1091/mbc.E02-04-0205}, author = {Dutcher, S. K. and Morrissette, N. S. and Preble, A. M. and Rackley, C. and Stanga, J.} } @article {1611, title = {Hox clusters and bilaterian phylogeny}, volume = {24}, year = {2002}, month = {2002//}, url = {http://dx.doi.org/10.1016/S1055-7903(02)00237-3}, author = {Balavoine, G. and Rosa, R. and Adoutte, A.} } @article {1612, title = {The abdominal-B-like gene expression during larval development of Nereis virens (polychaeta)}, volume = {115}, year = {2002}, month = {2002//}, url = {http://dx.doi.org/10.1016/S0925-4773(02)00113-2}, author = {Kulakova, M. A. and Kostyuchenko, R. P. and Andreeva, T. F. and Dondua, A. K.} } @article {1591, title = {The Schmidtea mediterranea database as a molecular resource for studying platyhelminthes, stem cells and regeneration}, volume = {129}, year = {2002}, month = {2002//}, url = {http://dx.doi.org/10.1242/dev.00167}, author = {Alvarado, A. S. and Newmark, P. A. and Robb, S. M. and Juste, R.} } @article {1609, title = {HOX genes in the sepiolid squid Euprymna scolopes: implications for the evolution of complex body plans}, volume = {99}, year = {2002}, month = {2002//}, url = {http://dx.doi.org/10.1073/pnas.042683899}, author = {Callaerts, P. and Lee, P. N. and Hartmann, B. and Farfan, C. and Choy, D. W. and Ikeo, K. and Fischbach, K. F. and Gehring, W. J. and Couet, H. G.} } @article {1579, title = {Not your father{\textquoteright}s planarian: a classic model enters the era of functional genomics}, volume = {3}, year = {2002}, month = {2002//}, url = {http://dx.doi.org/10.1038/nrg759}, author = {Newmark, P. A. and Alvarado, A. S.} } @article {1563, title = {Hox genes and the evolution of the arthropod body plan}, volume = {4}, year = {2002}, month = {2002//}, url = {http://dx.doi.org/10.1046/j.1525-142X.2002.02034.x}, author = {Hughes, C. L. and Kaufman, T. C.} } @article {1514, title = {The expression of neural-specific genes reveals the structural and molecular complexity of the planarian central nervous system}, volume = {116}, year = {2002}, month = {2002//}, url = {http://dx.doi.org/10.1016/S0925-4773(02)00134-X}, author = {Cebria, F. and Kudome, T. and Nakazawa, M. and Mineta, K. and Ikeo, K. and Gojobori, T.} } @article {1515, title = {Dissecting planarian central nervous system regeneration by the expression of neural-specific genes}, volume = {44}, year = {2002}, month = {2002//}, url = {http://dx.doi.org/10.1046/j.1440-169x.2002.00629.x}, author = {Cebria, F. and Nakazawa, M. and Mineta, K. and Ikeo, K. and Gojobori, T. and Agata, K.} } @article {39, title = {Terrestrial flatworm (Platyhelminthes: Tricladida: Terricola) diversity versus man-induced disturbance in an ombrophilous forest in southern Brazil}, journal = {Biodiversity and Conservation}, volume = {11}, number = {6}, year = {2002}, month = {2002}, pages = {1091-1104}, chapter = {1091}, url = {http://dx.doi.org/10.1023/A:1015865005604}, author = {Carbayo, Fernando and Leal-Zanchet, Ana Maria and Vieira, Emerson M.} } @article {694, title = {African planarians: Dugesia aethiopica sp. n. (Platyhelminthes, Tricladida) from Lake Tana (NW Ethiopia)}, journal = {Italian Journal of Zoology}, volume = {69}, number = {1}, year = {2002}, pages = {45-51}, publisher = {Taylor \& Francis}, abstract = {

A new species of Dugesia from East Africa is described as a first report of Platyhelminthes from Lake Tana. Dugesia aethiopica sp. n. is characterized by the shape of its bursa copulatrix; length, diameter, course, and opening of the bursal canal; opening of the oviducts; shape of the penis papilla; penial parenchymatic cavity. The taxonomic position of the new species within the D. gonocephala group is discussed in comparison with the other African and Madagascan species.

}, doi = {10.1080/11250000209356437}, author = {Giacinta Angela Stocchino and G. Corso and Manconi, Renata and Maria Pala} } @article {33, title = {Additions and corrections of the previous land planarian indices of the world (Turbellaria, Seriata, Ticladida, Terricola)}, journal = {Bull. Fuji Women{\textquoteright}s University}, volume = {40}, number = {14}, year = {2002}, month = {2002}, pages = {157-177}, chapter = {157}, author = {Masaharu Kawakatsu and Gen-Yu Sasaki and Robert E. Ogren and Eudoxia Maria Froehlich} }