02292nas a2200217 4500008004100000020001400041245008200055210006900137260005900206300001300265490000700278520157600285100001801861700002701879700002801906700002701934700001701961700001901978700002001997856005702017 2015 eng d a1932-620300aEvolutionary Analysis of Mitogenomes from Parasitic and Free-Living Flatworms0 aEvolutionary Analysis of Mitogenomes from Parasitic and FreeLivi aSan Francisco, CA USAbPublic Library of Sciencec2015 ae01200810 v103 a

Mitochondrial genomes (mitogenomes) are useful and relatively accessible sources of molecular data to explore and understand the evolutionary history and relationships of eukaryotic organisms across diverse taxonomic levels. The availability of complete mitogenomes from Platyhelminthes is limited; of the 40 or so published most are from parasitic flatworms (Neodermata). Here, we present the mitogenomes of two free-living flatworms (Tricladida): the complete genome of the freshwater species Crenobia alpina (Planariidae) and a nearly complete genome of the land planarian Obama sp. (Geoplanidae). Moreover, we have reanotated the published mitogenome of the species Dugesia japonica (Dugesiidae). This contribution almost doubles the total number of mtDNAs published for Tricladida, a species-rich group including model organisms and economically important invasive species. We took the opportunity to conduct comparative mitogenomic analyses between available free-living and selected parasitic flatworms in order to gain insights into the putative effect of life cycle on nucleotide composition through mutation and natural selection. Unexpectedly, we did not find any molecular hallmark of a selective relaxation in mitogenomes of parasitic flatworms; on the contrary, three out of the four studied free-living triclad mitogenomes exhibit higher A+T content and selective relaxation levels. Additionally, we provide new and valuable molecular data to develop markers for future phylogenetic studies on planariids and geoplanids.

1 aSolà, Eduard1 aÁlvarez-Presas, Marta1 aFrías-López, Cristina1 aLittlewood, Timothy, J1 aRozas, Julio1 aRiutort, Marta1 aEscriva, Hector uhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368550/00439nas a2200109 4500008004100000245011100041210006900152260002600221300001200247100001800259856005200277 1974 eng d00aA contribution to the phylogeny and biogeography of the freshwater triclads (Platyhelminthes, Turbellaria)0 acontribution to the phylogeny and biogeography of the freshwater aNew YorkbMcGraw-Hill a339-4011 aBall, Ian, R. uhttps://continenticola.myspecies.info/node/1378