@article {1899, title = {PlanMine 3.0{\textemdash}improvements to a mineable resource of flatworm biology and biodiversity}, journal = {Nucleic Acids Researchnar}, volume = {47}, year = {2018}, month = {2018}, pages = {D812 - D820}, abstract = {Flatworms (Platyhelminthes) are a basally branching phylum that harbours a wealth of fascinating biology, including planarians with their astonishing regenerative abilities and the parasitic tape worms and blood flukes that exert a massive impact on human health. PlanMine (http://planmine.mpi-cbg.de/) has the mission objective of providing both a mineable sequence repository for planarians and also a resource for the comparative analysis of flatworm biology. While the original PlanMine release was entirely based on transcriptomes, the current release transitions to a more genomic perspective. Building on the recent availability of a high quality genome assembly of the planarian model species Schmidtea mediterranea, we provide a gene prediction set that now assign existing transcripts to defined genomic coordinates. The addition of recent single cell and bulk RNA-seq datasets greatly expands the available gene expression information. Further, we add transcriptomes from a broad range of other flatworms and provide a phylogeny-aware interface that makes evolutionary species comparisons accessible to non-experts. At its core, PlanMine continues to utilize the powerful InterMine framework and consistent data annotations to enable meaningful inter-species comparisons. Overall, PlanMine 3.0 thus provides a host of new features that makes the fascinating biology of flatworms accessible to the wider research community.}, isbn = {0305-1048}, url = {https://doi.org/10.1093/nar/gky1070}, author = {Rozanski, Andrei and Brandl, Holger and Moon, HongKee and Grohme, Markus A and Henry, Ian and Rink, Jochen C and Martin-Duran, Jose M and H{\"u}ttner, Katja and Bartscherer, Kerstin} }