02050nas a2200265   4500008004100000022001400041245014100055210006900196260000900265300001000274490000700284520122200291653001201513653002101525653001901546653001901565653001401584100002001598700002201618700002501640700002201665700002101687700002401708856005201732       2013                        eng d  a0015-549700aBehavioral, morphological and histopathological effects of sublethal doses of quercetin on the species <i>Polycelis felina</i> (Dalyell)0 aBehavioral morphological and histopathological effects of sublet  c2013  a101-60 v613 a<p>The effect of quercetin was studied on the multi-eyed flatworm Polycelis felina (Daly.) in laboratory conditions. This is a very suitable test-organism available year-round in nature, easily maintained in the laboratory. The results showed that depending on the dose and recovery period quercetin caused locomotory (behavioral) changes in treated animals including aggregation in groups, resting and unsynchronized movements and twisting of particular body parts. Morphological changes in the form of depigmentation of certain body parts were the result of damage or deterioration ofreticular and parenchymal cells. Numerous basophilic bodies representing parts of damaged and decomposed cells were determined in the gastroderm between the third and seventh day after treatment. All histological preparations revealed significant deterioration of cellular material, and therefore a damaging effect of quercetin on the multi-eyed flatworm Polycelis felina (Daly.). We found an increased number of neoblasts and reticular cells on the third day after treatment, so we concluded that quercetin in the applied doses had a stimulating effect on cell division of neoblasts and reticular cells of treated flatworms.</p>
10aAnimals10aBehavior, Animal10aMotor Activity10aPlatyhelminths10aQuercetin1 aRajević, Nives1 aMatković, Helena1 aGregorović, Gordana1 aKovacević, Goran1 aKnezović, Lejla1 aKalafatić, Mirjana  uhttps://continenticola.myspecies.info/node/1722