Serotonin in the nervous system of the head region of the land planarian Bipalium kewense

Publication Type:Journal Article
Year of Publication:2003
Authors:M. C. Fernandes, Alvares, E. P., Gama, P., Silveira, M.
Volume:35
Issue:6
Pagination:479 - 486
Date Published:2003/12//
ISBN Number:0040-8166
Keywords:Cephalic ganglion, Immunohistochemistry, Land planaria, Nervous system, Plathelminthes, Serotonin
Abstract:

The presence and distribution of serotonin (5-hydroxytryptamine, or 5-HT) in the head region of the land planarian Bipalium kewense has been investigated by an indirect immunofluorescence technique combined with confocal scanning laser microscopy (CSLM), and also by immunogold labeling at ultrastructural level. Serotonin immunoreactivity (IR) was restricted to elements of the nervous system, such as the cerebral ganglion, and the peripheral nerve net. Most of 5-HT-immunoreactive neurons are at the periphery of the brain; they were identified as unipolar, bipolar, and multipolar neurons. The ultrastructural results using immunogold labeling confirm the location of 5-HT within electron-dense vesicles (50–120 nm in diameter), clustered both in the cell bodies and in their processes. The intense 5-HT-IR herein demonstrated for B. kewense adds new data to the poorly studied nervous system of land planarians.

URL:http://www.sciencedirect.com/science/article/pii/S0040816603000740
Short Title:Tissue and Cell
Tue, 2017-03-21 22:59 -- Eduard
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